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KMID : 0948320070070010008
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Konyang Medical Journal
2007 Volume.7 No. 1 p.8 ~ p.12
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The Endoscopic Findings and the Clinical Factors Associated with the Degrees of the Upper Gastrointestinal Endoscopic Lesion in Patients with Scrub Typhus
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Kim Sun-Moon
Choi Young-Woo
Kang Young-Woo
Kim Yong-Moon
Cheong Seung-Hyun
Lim Dae-Seung
Kim Yong-Seok
Lee Tae-Hee
Im Euyi-Hyeog
Huh Kyu-Chan
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Abstract
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Background/Aims: Scrub typhus, which is caused by Orientia tsutsugamushi, is an acute febrile disease. Endoscopic findings of scrub typhus have not well been reported. This study aimed to describe the characteristic endoscopic findings of scrub typhus and to find the clinical factors associated with the degrees of the upper gastrointestinal endoscopic lesion.
Methods: From September 2004 to December 2004, we performed upper endoscopy in case of 42 patients diagnosed as scrub typhus. We categorized endoscopic findings into two grades: that is, mild degree such as normal and
erythema; severe degree such as superficial hemorrhage, erosion, ulcer and ulcer bleeding. We evaluated whether
there was any correlation between various symptoms and signs known as clinical factors related to disease severity
and endoscopic findings.
Results: Mild endoscopic findings were 12 patients (28.6%) and severe findings were 30 patients (71.4%). Among
severe 30 patients, 29 patients (96.7%) were multiple lesions and their sizes was l ess than 1.0 cm. Abdominal symptom
was only associated with increased risk of severe endoscopic findings (p = 0.013).
Conclusion: The characteristic endoscopic findings of scrub typhus were multiple, less than 1.0cm sized superficial hemorrhage, erosions, and ulcer and ulcer bleeding. Abdominal symptom is only related to severe endoscopic lesions. Patients with abdominal symptom must be carried out endoscopy for diagnosis and management of gastrointestinal vasculitis.
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KEYWORD
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Scrub Typhus, Endoscopic Findings, Clinical Factors
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